Perceived differences in peer-to-peer accommodation before and after COVID-19: evidence from China. (Special Issue: The sharing economy in a post-pandemic world.)

Purpose: Based on text content analysis using big data, this study aims to explore differences in guest perceptions of peer-to-peer accommodations before and after COVID-19 to provide suggestions for the development of these properties in China postpandemic. Design/methodology/approach: A guest perception dictionary was established by collecting Ctrip customer reviews of peer-to-peer accommodations. After data cleaning, thematic word analysis and semantic association network analysis were used to explore perceptions and thematic differences before and after COVID-19. Findings: This research constructed a multidimensional framework of guest-perceived values for peer-to-peer accommodation in the context of COVID-19. The findings showed that the emphasis on functionality in peer-to-peer accommodation changed;perceived emotional values associated with peer-to-peer stays were more complex;perceived social values decreased, host-guest interactions were reduced and online communication became a stronger trend;tourist preferences for types of experiences changed, and people changed their destination selections;perceived conditional value was reflected in perceived risks, and the perceptions of environmental health, service and physical risks increased. Research limitations/implications: This research has constructed a multidimensional framework of tourist perceived value on the basis of peer-to-peer accommodation context and epidemic background and has thus shown the changes in tourist perceived value of peer-to-peer accommodation before and after COVID-19. Originality/value: To the best of authors' knowledge, this research constitutes the first attempt to explore the perceptual differences for peer-to-peer accommodations before and after COVID-19 based on an extensive data set of online reviews from multiple provinces of China.

Perceived differences in peer-to-peer accommodation before and after COVID-19: evidence from China

PurposeBased on text content analysis using big data, this study aims to explore differences in guest perceptions of peer-to-peer accommodations before and after COVID-19 to provide suggestions for the development of these properties in China postpandemic.Design/methodology/approachA guest perception dictionary was established by collecting Ctrip customer reviews of peer-to-peer accommodations. After data cleaning, thematic word analysis and semantic association network analysis were used to explore perceptions and thematic differences before and after COVID-19.FindingsThis research constructed a multidimensional framework of guest-perceived values for peer-to-peer accommodation in the context of COVID-19. The findings showed that the emphasis on functionality in peer-to-peer accommodation changed;perceived emotional values associated with peer-to-peer stays were more complex;perceived social values decreased, host–guest interactions were reduced and online communication became a stronger trend;tourist preferences for types of experiences changed, and people changed their destination selections;perceived conditional value was reflected in perceived risks, and the perceptions of environmental health, service and physical risks increased.Research limitations/implicationsThis research has constructed a multidimensional framework of tourist perceived value on the basis of peer-to-peer accommodation context and epidemic background and has thus shown the changes in tourist perceived value of peer-to-peer accommodation before and after COVID-19.Originality/valueTo the best of authors' knowledge, this research constitutes the first attempt to explore the perceptual differences for peer-to-peer accommodations before and after COVID-19 based on an extensive data set of online reviews from multiple provinces of China.

Health tourism in China: a 40-year bibliometric analysis

Purpose>The purpose of this study is to systematically analyze the evolution of health tourism development, identify relevant themes and segments of health tourism research and offer future research directions and practical implications for academic researchers and tourism practitioners worldwide using China as an example.Design/methodology/approach>Using a bibliometric analysis, the present study comprehensively analyzes the theme, segments and the evolution of health tourism research over the past 40 years in China.Findings>Major findings show that health tourism research in China could be divided into four stages with different characteristics, and three segments, including wellness tourism, health and wellness tourism and medical tourism. Findings also reveal the trend of health tourism development tends to be industrialized, diversified and systematic under the guidance of recent policies. Theoretically, based on the theoretical framework developed by Hall (2011), the present study contributes to the establishment and extension of the framework for health tourism within the context of China. Practically, findings can provide health tourism-related policy implications for the future development of health or health sector-integrated tourism.Research limitations/implications>The study proposes possible collaboration between government and academia in terms of health tourism-related policy formulation.Originality/value>Through 40-year bibliometric analysis of health tourism evolution in China, the present study explores the main themes of health tourism development, identifies the segments of health tourism and analyzes the development stages of health tourism. Findings should be of use to international readers to better understand the uniqueness of health tourism development and find out possible future health tourism development research directions. As a result, major contributions of this paper are the comprehensive analysis of the evolution of health tourism research and the implications on other countries and regions to adopt a pragmatic approach to explore the trend and unique characteristics of health tourism for future development.

Outpatient human coronavirus associated conjunctivitis in India.

BACKGROUND: Viral conjunctivitis (pink eye) can be highly contagious and is of public health importance. There remains significant debate whether SARS-CoV-2 can present as a primary conjunctivitis. The aim of this study was to identify pathogens associated with outpatient infectious conjunctivitis during the COVID-19 Delta surge. METHODS: This prospective study was conducted in the spring and summer months of 2021. 106 patients with acute conjunctivitis who presented to the Aravind Eye Center in Madurai, India were included. One anterior nasal swab and one conjunctival swab of each eye were obtained for each enrolled patient. Samples were subsequently processed for unbiased metagenomic RNA deep sequencing (RNA-seq). Outcomes included clinical findings and codetection of other pathogens with SARS-CoV-2 in patients with conjunctivitis. RESULTS: Among the 13 patients identified with human coronavirus RNA fragments in their swabs, 6 patients had SARS-CoV-2 infection, 5 patients had coinfections of SARS-CoV-2 and human adenovirus (HAdV), 1 patient had a coinfection with human coronavirus OC43 and HAdV, and 1 patient had a coinfection of Vittaforma corneae and SARS-CoV-2. 30% had bilateral disease and symptoms on presentation. Petechial hemorrhage was noted in 33% of patients with SARS-CoV-2 infection. No patients with SARS-CoV-2 or SARS-CoV-2 and HAdV infections had subepithelial infiltrates on presentation. All patients denied systemic symptoms. CONCLUSIONS: Among the patients presented with conjunctivitis associated with human coronavirus infection, over 50% of the patients had co-infections with other circulating pathogens, suggesting the public-health importance of broad pathogen testing and surveillance in the outpatient conjunctivitis population.

Deep sequencing analysis of clinical samples from patients with acute infectious conjunctivitis during the COVID-19 delta surge in Madurai, India.

BACKGROUND: Seasonal outbreaks of infectious conjunctivitis remain a public health issue. Determination of outbreak etiologies in the context of a worldwide pandemic may provide useful information to guide public health strategies. The aim of this study was to identify pathogens associated with outpatient infectious conjunctivitis during the COVID-19 Delta surge. METHODS: This prospective study was conducted from April 2021 to September 2021. All outpatients presenting to the Aravind Eye Center (Madurai, India) with signs and symptoms consistent with acute infectious conjunctivitis were eligible. Three swabs were obtained from each participant: one from each conjunctiva and one from the anterior nares. Samples were processed for metagenomic RNA deep sequencing (RNA-seq). RESULTS: Samples from 106 study participants were sequenced. The most common presenting symptoms were tearing (86%) and itching (71%). Preauricular lymphadenopathy was present in 38% of participants. 20% of participants had close contacts with similar symptoms. Systemic symptoms such as coughing, runny nose, vomiting or diarrhea were uncommonly reported. 60% of all participants used some medicated eye drops upon enrollment. 75% of study participants demonstrated infection with human adenovirus D (HAdV-D). 11% of conjunctivitis was associated with SARS-CoV-2. 15% had no definitive pathogen detected. 8% of all participants had codetection of more than one pathogen on RNA-seq. CONCLUSIONS: During the COVID-19 Delta surge in India, HAdV-D was the most common pathogen associated with infectious conjunctivitis. SARS-CoV-2 was the second most common associated pathogen. Seasonal surveillance may be necessary for the determination of emerging and reemerging pathogens responsible for infectious conjunctivitis.

Health Tourism Evolution: A Review Based on Bibliometric Analysis and the China National Knowledge Infrastructure Database

To systematically understand the evolution of health tourism in China, the present study visually analyzes the theme evolution and frontiers of Chinese health tourism research on the basis of the China National Knowledge Infrastructure (CNKI) database through bibliometric analysis. The findings reflect the existence of diverse clustering themes in health tourism research, and the formation time of each theme is different. The findings also indicate that the change in the theme is led by government policy. Theoretically, the findings of the present study can, on the one hand, contribute to the health tourism literature by comprehensively exploring and summarizing the themes and topics of health tourism development in China since its appearance (i.e., 1981), and, on the other hand, provide references for future health tourism exploration directions. Findings of the present study can provide references for effective future development directions of the health tourism industry.

A Proposed DISE Approach for Tourist Destination Crisis Management

Novel coronavirus (COVID-19) has had a huge impact on the global tourism industry over the past couple of years. Most previous studies investigated tourism crises after the pandemic period. Hence, to minimize the research gap, the present study investigates the impact of COVID-19 on tourism during the pandemic period. By assessing this impact, this paper proposes a D (big data) I (impact module) S (strategy module) E (evaluation module) model to cope with the crisis in order to bring about feasible implications for tourism practitioners and governments. This paper is to provide real-time destination management adjustments. This model is based on a crisis management framework and governance theory through retrieving big data from China Unicom and major travel information delivery sources. The major finding shows that the detailed time points of pandemic information release in the early stage of crisis. In conclusion, through proposing a DISE model, the present study assesses the impact of the major emergency public health crisis, assists destination managers in adjusting tourism-related policy and reflects the priority of recovering tourism after the crisis for effective tourist destination management.

Perception, Reaction, and Future Development of the Influence of COVID-19 on the Hospitality and Tourism Industry in China.

The present study examined the perception, reaction (i.e., possible measures), and future development from the perspectives of hotel and tourism practitioners and experts to investigate the influence of coronavirus disease 2019 (i.e., COVID-19) on the hospitality and tourism industry in China. After conducting 58 in-depth interviews among hotel and tourism practitioners and experts, feasible and practical measures were proposed to reduce such influence and predict the future development of China's hospitality and tourism industry. Findings indicate that the influence of COVID-19 on the industry is perceived mainly through the pandemic's economic and social effects. Possible measures that can be adopted for the recovery of China's hospitality and tourism industry include the following aspects: government financial support, employee relationship management and electronic (e)-training, business marketing management, and industry co-operation network. A Perception-Reaction-Predication (PRP) crisis model is also proposed.

Effect of Oral Azithromycin vs Placebo on COVID-19 Symptoms in Outpatients With SARS-CoV-2 Infection: A Randomized Clinical Trial.

Importance: Azithromycin has been hypothesized to have activity against SARS-CoV-2. Objective: To determine whether oral azithromycin in outpatients with SARS-CoV-2 infection leads to absence of self-reported COVID-19 symptoms at day 14. Design, Setting, and Participants: Randomized clinical trial of azithromycin vs matching placebo conducted from May 2020 through March 2021. Outpatients from the US were enrolled remotely via internet-based surveys and followed up for 21 days. Eligible participants had a positive SARS-CoV-2 diagnostic test result (nucleic acid amplification or antigen) within 7 days prior to enrollment, were aged 18 years or older, and were not hospitalized at the time of enrollment. Among 604 individuals screened, 297 were ineligible, 44 refused participation, and 263 were enrolled. Participants, investigators, and study staff were masked to treatment randomization. Interventions: Participants were randomized in a 2:1 fashion to a single oral 1.2-g dose of azithromycin (n = 171) or matching placebo (n = 92). Main Outcomes and Measures: The primary outcome was absence of self-reported COVID-19 symptoms at day 14. There were 23 secondary clinical end points, including all-cause hospitalization at day 21. Results: Among 263 participants who were randomized (median age, 43 years; 174 [66%] women; 57% non-Hispanic White and 29% Latinx/Hispanic), 76% completed the trial. The trial was terminated by the data and safety monitoring committee for futility after the interim analysis. At day 14, there was no significant difference in proportion of participants who were symptom free (azithromycin: 50%; placebo: 50%; prevalence difference, 0%; 95% CI, -14% to 15%; P > .99). Of 23 prespecified secondary clinical end points, 18 showed no significant difference. By day 21, 5 participants in the azithromycin group had been hospitalized compared with 0 in the placebo group (prevalence difference, 4%; 95% CI, -1% to 9%; P = .16). Conclusions and Relevance: Among outpatients with SARS-CoV-2 infection, treatment with a single dose of azithromycin compared with placebo did not result in greater likelihood of being symptom free at day 14. These findings do not support the routine use of azithromycin for outpatient SARS-CoV-2 infection. Trial Registration: ClinicalTrials.gov Identifier: NCT04332107.

Reduction of coronavirus burden with mass azithromycin distribution. (COVID special issue #2.)

We evaluated the potential antiviral effects of azithromycin on the nasopharyngeal virome of Nigerien children who had received multiple rounds of mass drug administration. We found that the respiratory burden of non-severe acute respiratory syndrome coronaviruses was decreased with azithromycin distributions.